Structure and Mechanism-Guided Design of Dual Serine/Metallo-Carbapenemase Inhibitors | Journal of Medicinal Chemistry
Forging Odd-Membered Rings: Palladium-Catalyzed Asymmetric Cycloadditions of Trimethylenemethane | Accounts of Chemical Research
Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate | ACS Medicinal Chemistry Letters
Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles | ACS Medicinal Chemistry Letters
Synthetic RNA Modulators in Drug Discovery | Journal of Medicinal Chemistry
Development of Novel Epoxyketone-Based Proteasome Inhibitors as a Strategy To Overcome Cancer Resistance to Carfilzomib and Bortezomib | Journal of Medicinal Chemistry
Discovery of APD371: Identification of a Highly Potent and Selective CB2 Agonist for the Treatment of Chronic Pain | ACS Medicinal Chemistry Letters
Journal of Natural Products Special Issue Honors Drs. Rachel Mata and Barbara N. Timmermann - ACS Axial | ACS Publications
MOARF, an Integrated Workflow for Multiobjective Optimization: Implementation, Synthesis, and Biological Evaluation | Journal of Chemical Information and Modeling
Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria | Journal of Medicinal Chemistry
Synthesis of Thymoquinone–Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents | ACS Medicinal Chemistry Letters
Discovery of Novel BRD4 Ligand Scaffolds by Automated Navigation of the Fragment Chemical Space | Journal of Medicinal Chemistry
Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS) | Journal of Medicinal Chemistry
Multifunctional Carrier Based on Halloysite/Laponite Hybrid Hydrogel for Kartogenin Delivery | ACS Medicinal Chemistry Letters
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity | Journal of Medicinal Chemistry
Design and Synthesis of Potent Quinazolines as Selective β-Glucocerebrosidase Modulators | Journal of Medicinal Chemistry
Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase | ACS Medicinal Chemistry Letters
Dehydrozingerone Inspired Styryl Hydrazine Thiazole Hybrids as Promising Class of Antimycobacterial Agents | ACS Medicinal Chemistry Letters
Stabilization of Nanoparticles Produced by Hydrogenation of Palladium–N-Heterocyclic Carbene Complexes on the Surface of Graphene and Implications in Catalysis | ACS Omega
Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3-Kinase (PI3K)-γ Inhibitors | Journal of Medicinal Chemistry
Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy | Journal of Medicinal Chemistry
Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit | ACS Medicinal Chemistry Letters
Synthesis and Cell-Based Activity of a Potent and Selective Protein Tyrosine Phosphatase 1B Inhibitor Prodrug | Journal of Medicinal Chemistry
Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis | Journal of Medicinal Chemistry
